Alcoholism and the Brain
Alcoholics have smaller brain volumes, probably due to the toxic effects of ethanol that causes the brain to shrink more with aging - but a new study shows that the brains of children of alcohol-dependent parents have reduced intracranial volume before they even take a drink.

The study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), is the first to demonstrate that for children of alcoholics, brain size is affected before the onset of alcohol dependence.
Intracranial volume, or ICV, was found to be about 4 percent smaller in adult children of alcoholic parents than in adults who had no family history of alcoholism. IQ scores in alcoholic individuals whose parents were also alcoholic were found to average 5.7 points lower than in alcoholics whose parents were not alcohol-dependent.
The authors note that a possible implication of their findings is that the increased risk for alcoholism among children of alcoholics may be due to a genetic or environmental effect, or both, related to reduced brain growth.
“Although ICV is known to be influenced primarily by genetic factors,†says Dr. Daniel Hommer, senior author of the study,“many studies have found that living in an enriched environment promotes central nervous system growth and development. It seems likely that alcoholics, in general, are raised in less than optimal environments and thus that genetics and environment both contribute to the smaller ICV observed in family history positive alcoholics.â€
Study Finds Reduced Brain Growth in Alcoholics with Family Drinking History




